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Weight-loss medications that may interact with alcohol, whether directly or indirectly, include: GLP-1 agonists, such as Wegovy (semaglutide) and Saxenda (liraglutide) Sympathomimetic appetite suppressants, such as Adipex-P (phentermine) and Tenuate (diethylpropion) Combination medications, including Contrave (bupropion and naltrexone) Lipase inhibitors, like Alli (orlistat) SGLT2 inhibitors, such as Invokana (canagliflozin) and Farxiga (dapagliflozin) Melanocortin 4 receptor (MC4R) agonists, such as Imcivree (setmelanotide) Besides the risk that alcohol can interact with medications, its a good idea for other reasons to steer clear of drinking if youre trying to lose weight
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