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[1] [2] As a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, Zepbound works by mimicking naturally occurring incretin hormones that regulate appetite, food intake, and glucose metabolism, though the exact mechanism for weight loss is not fully understood

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In mammals, ferroptosis has been implicated in diverse pathologies, including neurodegenerative diseases, stroke, traumatic brain injury and kidney degeneration, as well as in carcinogenesis, where it may exert a tumor-suppressor function

[1] [9] Any blood pressure elevations observed during semaglutide therapy should prompt evaluation for alternative causes rather than automatic attribution to the medication itself