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Sun Y, Ahmed S, Smith RG

Tissue Repair and Recovery Research Tissue repair is one of the more substantiated research areas for IGF-1 LR3, largely because the underlying mechanisms collagen synthesis stimulation and satellite cell recruitment are directly relevant to muscle and connective tissue recovery

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Studies by Gan and colleagues showed that GH can promote the formation of GHR/JAK2/IGF-IR complex to facilitate GHR signaling in osteoblasts (71), indicating a novel complementation between GHR and IGF-IR signaling, which could be a basis for some IGF-IR-dependent GH actions

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