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[DOI] [PubMed] [Google Scholar] 79.Rushworth SA, MacEwan DJ, OConnell MA

In our previous study, we developed a method for detecting lipid-derived radicals based on their reaction with NBD-Pen and carbon-centered radicals, combined with LC-MS/MS analysis 15

The fact that CysC is sulfenylated in all OAS together with the observed persulfidation of three OAS isoforms may suggest a two-step mechanism in which sulfenylation precedes persulfidation, i.e., when sulfenic acids react with H 2 S

And therefore, Lyme patients are notorious for having low levels of these immune factors

C5a can activate pro-inflammatory signaling pathways such as NF-B and upregulate the expression of adhesion molecules on endothelial cells or macrophages, thereby promoting the adhesion of leukocytes to the endothelium and the recruitment of inflammatory cells (120)