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Key parameters assessed include basal and maximal respiratory capacity, ATP-linked respiration, spare respiratory capacity, basal glycolysis, and glycolytic reserve

Laboratory studies demonstrate that combinations of improved senolytic peptides (such as ES2, which shows 3-7 times greater efficacy than FOXO4-DRI) with chemotherapeutic agents like Dabrafenib result in greater elimination of both cancer and senescent cells

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A comparative study has demonstrated that neohesperidin dihydrochalcone (NHDC), an artificially structurally modified flavonoid, exhibits superior efficacy in mitigating ovalbumin-induced food allergy in mice compared to its precursor compound, neohesperidin (NH)