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[ Acknowledgements We thank Sven Paul, Institute of Animal Breeding and Husbandry, University of Kiel, for revising the manuscript, Matthias Leippe, Department of Zoophysiology, University of Kiel, for helpful information and Virbac for providing the picture "Internal organs of the horse"

Dead space compensation Every syringe has dead space, the volume of solution that remains in the hub and needle after the plunger is fully depressed

One note:alcohol consumption can drastically deplete B vitamins (especially thiamine and folate)

10.1016/s0149-2918(03)90096-8 7 BorM