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In such circumstances: Contact emergency services (999) or attend the nearest Accident & Emergency department Call NHS 111 for urgent but non-life-threatening concerns Contact your local NHS urgent mental health helpline (search online for 'NHS urgent mental health helpline' and your location) Call the Samaritans (116 123, available 24/7) for immediate emotional support Do not leave the person alone if they are at immediate risk For non-emergency concerns about mood changes whilst taking GLP-1 agonists, patients should contact their GP or diabetes specialist nurse within 2448 hours

Cutolo M, Nikiphorou E

Consequently, several therapeutic interventions have already been conducted to assess the effects of butyrate supplementation in diabetic patients and patients with obesity and metabolic syndrome (Table 1)

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