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Melatonin improves oxidative stress parameters measured in the blood of elderly type 2 diabetic patients
2.7 kg) albeit with a worse gastrointestinal side effect profile [57]
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3.1 Alternative nutrient-sensing mechanisms Some nutrients stimulate intestinal hormone secretion independent of taste receptors, via pathways involving other GPCR or nutrient transporters (95, 96): Stomach: Calcium-sensing receptor (CaSR) and GPRC6A detect a broad range of amino acids and calcium, promoting gastrin and somatostatin release (89, 97)
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