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Relative to the wild-type enzyme, mutation of residue 15 to serine or alanine in UGT74F2 did not lessen the specific activity for SGE formation, but did increase the formation of SAG

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The Journal of clinical endocrinology and metabolism 99 , E13061310, (2014)

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Reported observations include: Temporary injection site irritation Mild redness Temporary swelling Local discomfort Mild headache Researchers continue examining long-term biological responses across different laboratory models