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Realistic outcome expectations Mechanistic success without clinical transformation: Preserving 40% more ganglion cells represents mechanistic success

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Methods We searched MEDLINE (19962014), EMBase (19742014), and CENTRAL (May 2014) up to June 27, 2014 for randomized controlled trials (RCTs) comparing ALC with placebo or other active medications in diabetic and non-diabetic PNP patients that reported the change of pain using visual analogue scale (VAS)