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Studies examining over 200 pregnancies with first-trimester GLP-1 exposure have not found elevated rates of major birth defects compared to other diabetes medications

PMID: 32448729 12 Systemic primary carnitine deficiency with hypoglycemic encephalopathy

Interestingly, Retatrutides nausea rate of approximately 28% at higher doses actually falls below Semaglutides 44% rate despite superior efficacy

The Retatrutide vs Tirzepatide comparison will become substantially more conclusive once Phase 3 enrollment and readout are complete, which researchers anticipate in 2026-2027

Damit knnte der Pharmakonzern erstmals eine oral verfgbare GLP-1-Therapie auf den Markt bringen, die klinisch vergleichbare Ergebnisse zu den bisher etablierten injizierbaren GLP-1-Prparaten bietet