(2) randomized controlled trials assessing safety and efficacy profiles of combined SGLT2 inhibitor and high-dose polyphenol interventions in DKD populations
doi: 10.1371/journal.pone.0222993 17 KirszbergC.RumjanekV
However, ROS can also trigger cell senescence and death, acting as an anti-tumorigenic agent (112)
Non-alcoholic fatty liver disease is the most common chronic hepatic disease at the worldwide level [1,2], and is defined as increased intrahepatic fat accumulation, in the absence of risk factors for liver disease, such as alcohol abuse, steatogenic medications, and other causes of chronic liver disease [2]
There are shared characteristics regarding ferroptosis and various cutaneous diseases in terms of pathophysiological mechanisms, such as oxidative stress associated with iron metabolism disorder and accumulated lipid peroxides