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therapies are largely symptomatic and directed at palliation rather than correction of the underlying immune dysfunction

Within 24 h of administering 500 mL of AI, cumulative urinary excretion of AS-IV reached 3.91%, indicating linear pharmacokinetics within a 200500 mL dose range, with no accumulation observed following once-daily administration of AI (Xu et al., 2013)

2016 May 10;6:e807

for longerterm storage, freezing at approximately 20 C is recommended to preserve peptide integrity

258 With aging, the function of the immune system gradually decreases, and the ability of immune cells to recognize and eliminate tumor cells weakens, thereby allowing cancer cells increased opportunities to evade immune surveillance