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These analogs are beneficial to diabetes patients in numerous ways as they work by enhancing glucose-dependent insulin secretion, suppressing elevated glucagon secretion, slowing gastric emptying, and suppressing appetite

10.1016/j.jhep.2023.08.021 6

Meanwhile, NRF2 activated heme oxygenase-1 (HO-1) expression, which encouraged Fe 2+ buildup in LIP and iron release from hemoglobin, as well as iron apoptosis development

Currently available pharmaceutical interventions for managing T2DM consist of sulphonylureas, insulin, thiazolidinediones, glucosidase inhibitors, sodium/glucose cotransporter 2 (SGLT2) inhibitors, and metformin