Pros and Cons Benefits: Proven reduction in HbA1c and cardiovascular risk in diabetic patients Significant, sustained weight loss observed in clinical trials Once-weekly dosing improves adherence compared to daily medications Minimal impact on heart rate at therapeutic doses Drawbacks: Common side effects include nausea, vomiting, diarrhea, and constipation, especially during dose escalation Potential risk of pancreatitis, gallbladder disease, and suicidal thoughts (rare) High cost without insurance
But to allow your whole health decision to be determined by the risk of breast cancer is ridiculous
This means it mimics the natural hormone GLP-1 produced in the gut, increasing insulin production, lowering blood sugar, and curbing appetite
An oral option for obesity could expand the addressable population
This is why stacking semaglutide with tirzepatide makes no sense, you would likely experience severe GI distress without additional benefit
