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They are not Direct Meds-specific thresholds they reflect the clinical standards applied by any compliant GLP-1 prescribing program

Clinical trials and post-market data show that pancreatitis is a rare but documented adverse event in patients taking GLP-1 drugs, occurring in approximately 0.1% of users

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doi: 10.1136/oemed-2019-106012 7

If you feel either area needs more time, you can inject the upper arm, then rotate back to the stomach on your fourth week