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Additionally, a recent study published in Nature estimates that, without effective mitigation, extreme temperatures could result in an additional 2.3 million deaths in European cities by the end of the century (Masselot et al., 2025)

This paradoxical reaction is not fully understood but is thought to be related to individual metabolic responses

Peer-reviewed and received in revised form 11 January 2022

Results are normally seen within 3 to 6 weeks

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