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The pattern across these concerns: the most alarming-sounding risks (cancer, vitiligo, weight gain) have little to no scientific support for standard oral supplementation, while the more mundane, less-discussed side effect (mild headache) is the one with actual documented occurrence
To evaluate the robustness of the evidence, we conducted a sensitivity analysis by excluding one study at a time from the meta-analysis to observe changes in the overall pooled results
Ferroptosis is fundamentally controlled by lipoxygenase-driven LPO, which is limited by GPX4 and driven by cellular iron availability 1
One of these SCFAs is called butyrate, and butyrate raises GLP-1