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Unlike exogenous recombinant human growth hormone (rhGH), sermorelin stimulates physiologic GH production while preserving feedback regulation via somatostatin and IGF-1 pathways

The consent must accurately characterize the compound as an unapproved bulk drug substance (not as an approved drug used off-label), the evidence base and its limitations, known and theoretical risks, alternatives considered, the monitoring plan, and the patients ability to decline or discontinue

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Dosing, administration routes, timing, cycling, and storage all affect outcomes in ways that the research literature does not always make explicit

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