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The Two States of Glutathione In the body, this molecule exists in two different states: Reduced Glutathione (GSH): This is the active, functional state

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doi:10.1210/jc.2005-1536 (source) Sackmann-Sala L, Ding J, Frohman LA, Kopchick JJ

FIGURE 6 In summary, GPX7 is an essential sensor for oxidative stress and endoplasmic reticulum stress ( 2.8 GPX8 Glutathione peroxidase 8 (GPX8) is a type II transmembrane protein with rare structural features that consists of 209 amino acids (Yoboue et al., 2017)