Stigmasterol alleviates interleukin-1beta-induced chondrocyte injury by down-regulatingsterol regulatory element binding transcription factor 2 to regulateferroptosis
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Zeng J, Soragni A, Ishizawa J, Ruvolo V, Benton CB, McQueen T, Ruvolo P, Qi Y, Su X, Burks J, Eisenberg DS, Andreeff M
Specifically, mtROS is believed to induce the dissociation of thioredoxin-interacting protein (TXNIP) from thioredoxin
Furthermore, iron deficiency anemia may disrupt lipid metabolism and vascular endothelial function, further elevating CHD risk