J Control Release 235:3447 Sarathkumar E, Victor M, Menon JA, Jibin K, Padmini S, Jayasree RS (2021) Nanotechnology in cardiac stem cell therapy: cell modulation, imaging and gene delivery
The 545 amino acid isoform a protein is inactive but post-translational processing results in a 515 amino acid functional protein containing an acetylated alanine residue at the N-terminus
When this pathway is less efficient, glutathione demand often exceeds supply
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It promotes mitochondrial fusion and cell survival by upregulating mitochondrial prohibitin 2 and optic atrophy 1 protein levels (72)