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Determinants of colonic barrier function in inflammatory bowel disease and potential therapeutics

En un estudio clnico multicntrico europeo, la suplementacin con L-carnitina (en forma de propionil-L-carnitina a 2 g/da durante 12 meses) en pacientes con claudicacin moderada a severa relacionada con la distancia mxima recorrida y la calidad de vida percibida logr una mejora significativa en comparacin con los pacientes que solo recibieron placebos

GLP-1 (7-36) has a short half life of less than 2 minutes, and like GIP, is rapidly degraded by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles

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