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In rare monogenic disorders such as HD, evidence from patients with HD and rodent models suggests that dysfunctional BDNF-TrkB signalling is involved in the disorder development 10

CSL Seqirus Sector: Influenza vaccines HQ: Holly Springs, NC Year Founded: 2015 Key Leaders: Gordon Naylor, CEO and Managing Director Number of Employees: 25,000+ Stage: Subsidiary of CSL Limited (private) Financial Snapshot: Market cap for the parent company was $38.48 billion as of February 2024

Macrophages in chronic liver failure: diversity, plasticity and therapeutic targeting

1a) or glutamine starvation (Extended Data Fig

higher doses do not guarantee bigger benefits and can increase side-effect risk