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A proof-of-concept phase 2 study compared two doses (50 and 150 mg) of this first-in-class drug to placebo in PD patients on dopaminergic treatment with an OFF-time of at least 2 h [152]

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MTHFR MTHFR gene In humans, the MTHFR resides on chromosome 1 location p36.3 and was originally described as containing 12 exons as shown in Fig

In summary, although this study aims to comprehensively review the pathogenesis of ferroptosis in different kidney diseases, we still believe it has some shortcomings, such as the limitations of research perspectives