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After ovulation, HCG supports the corpus luteum so it continues to produce progesterone and estrogen, hormones necessary to maintain the uterine lining for implantation and early pregnancy

References: Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes Autologous chondrocyte implantation (ACI) is a procedure used to treat articular cartilage injuries and prevent the onset of post-traumatic osteoarthritis

A conspicuous upregulation of ZIP14 was observed in dystrophic muscles from metastatic cancer

But production declines with age, stress, illness, toxin exposure, and poor nutrition

Thus, estrogen might prevent bone loss by enhancing oxidant defenses in bone