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Co-staining for tdTomato with GCG revealed increased overlap in HFD-fed mice compared with ND-fed controls, suggesting that cells undergo transdifferentiation into cells in the islets of HFD-induced diabetic mice

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Research indicates that CD40 likely plays a critical role in inducing the production of autoantibodies and immunoglobulins by autoreactive B cells, which in turn contributes to the pathogenesis of SLE (148)

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2024 systematic review, Cohen et al