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This trial helped redefine expectations for pharmacologic obesity treatment and provided a benchmark against which newer multi-receptor therapies are often compared

Values expressed as mean SD Relative changes (%) from baseline (T0) to 90 days (T1) in l-arginine compared to placebo group Discussion Historically, consistent effort was spent in the search of pharmacological and/or more physiological alternatives in the treatment of ED

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Insulin Secretion A significant advantage of this dual action is enhanced insulin secretion