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Thus, the -glutamyl cycle, apart from explaining the synthesis and degradation of glutathione, may serve as a generator of signals to activate amino acid transport into cells (2, 75)

To estimate how the peptide levels during the first 12 months were associated with the fasting C-peptide/glucose ratio at 24 months, a linear slope for each peptide and each individual over the first four visits was calculated using linear regression models

Dietary interventions, particularly the intake of omega-3 FAs, are considered potential adjunctive methods for mitigating the effects of comorbid depression and lung cancer, as omega-3 FAs are believed to have mood-regulating benefits (166, 223)