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In addition, reduced appetiteone of the primary mechanisms of these medicationscan lead to: Inadequate protein intake Lower overall nutrient intake Increased risk of micronutrient deficiencies These factors may negatively impact muscle mass, metabolic rate, and long-term weight maintenance if not addressed (Mechanick et al., 2020

Method Enzymol 186, 448457 (1990)

Supervision by a qualified healthcare provider is critical to both the success of the weight loss journey and the safety of the patient

This reduction in weight is largely due to the medications effects on appetite regulation, insulin sensitivity, and slower gastric emptying 3,8

The free B12 binds to a protein called R-binder (haptocorrin) in the stomach