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Rand BC, Penn-Barwell JG, Wenke JC

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102 In placebo-controlled trials, one single-blind 103 and one double-blind 104 trial, nortriptyline was found to significantly reduce depression severity, tinnitus-related disability, and loudness in patients with severe depressive symptoms

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Data from a randomized, double-blind, placebo-controlled, parallel, three-arm study with 60 women indicated that 250 mg of glutathione per day for 12 weeks resulted in significant reductions in wrinkles and increased skin elasticity