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In rodent studies it has shown rapid antidepressant-like activity and, relevant to cognition, has been associated with increased markers of neurogenesis and synaptogenesis in the hippocampus, including effects linked to BDNF signaling

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McCracken JT, Anagnostou E, Arango C, Dawson G, Farchione T, Mantua V, et al

Long-term data is important in view of the fact that those individuals, predominantly women, who seek treatment need to be managed over longer periods of time to maintain effect and as part of their personal preference and self-esteem