Heat changes tendon biology, training load tolerance shifts, and overuse injuries to the Achilles, plantar fascia, and patellar tendon are well-documented [British Journal of Sports Medicine, 2019]
If yes, do not use it
Sources : Pekala J, Patkowska-Sokoa B, Bodkowski R, et al
Important safety considerations include a boxed warning for thyroid C-cell tumors, contraindications in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and risks of pancreatitis, gallbladder disease, hypoglycemia (when used with insulin or insulin secretagogues), and acute kidney injury
Sections were washed three times for 5 min each in 0.1 M PBS, followed by incubation in 50% ethanol for 30 min