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Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription

Am J Epidemiol 1989

This study found that in animals treated with 2-Aminobicyclo [2, 2, 1] heptane-2-carboxylic acid (BCH), a nonmetabolic analogue of leucine, the renal arteriovenous ammonia level change was greater than in the liver, indicating that hyperammonemia in GDH-HI patients is mainly induced due to increased renal ammonia production, instead of abnormalities in urea synthesis in the liver

GSH plays a pivotal role in maintaining intracellular redox balance by detoxifying peroxides and other oxidized compounds

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