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4.6 Carotenoids Carotenoids are powerful antioxidant compounds involved in ROS scavenging and in protection of skin barrier integrity

The absence of hormetic triggers can also alter the activity of PGC-1, which could result in metabolic dysfunction of tissues, leading to the development of various metabolic diseases (Vandenbeek et al., 2018)

Body composition changes begin

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L-DOPA alone contributed to strong recovery of motion phenotypes during initial phase, however, its effect lagged in aged flies which showed movement defects similar to untreated park 13 mutants (Fig