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40 rats that developed T2DM were randomly divided into four groups (n = 10 per group): diabetic group (D), diabetic exercise group (DE), diabetic MOTS-c group (DM), and diabetic exercise + MOTS-c group (DME)

Iacopino and Licausi, 2020)

It is commonly employed in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems

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doi: 10.1016/S2213-8587(23)00058-X 169 RubinoFCummingsDEEckelRHCohenRVWildingJPHBrownWAet al