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Many patients in the trial were also receiving standard-of-care therapies for their underlying cardiovascular disease, with 90.1% of patients taking lipid-lowering medications, 86.2% antiplatelets, 70.2% beta-blockers, 45.0% ACE inhibitors and 29.5% ARBs

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52 The trial aims to enroll 20 participants to analyze proximal tubular natriuresis with combination therapy and monotherapy as primary outcomes, and measured glomerular filtration rate, eGFR, and urinary albumin excretion as secondary outcomes