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Platinum-containing chemotherapies induce cell death in part by depleting glutathione and inactivating glutathione peroxidase [21], explaining the synergy between carboplatin and GPX4-suppressed cells in vitro and in vivo
It also helps form red blood cells that carry oxygen throughout the body, which is why a deficiency can cause symptoms such as fatigue, weakness, and anemia
Genomic analysis identifies new drivers and progression pathways in skin basal cell carcinoma
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