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It has been shown, for example, that experimentally inducing a specific dysfunction within the mitochondria (involving inner-membrane Complex I) of a specific kind of neuron (the type that uses dopamine as a neurotransmitter) in a specific part of the brain (the substantia nigra, and likely just the pars compacta part of it) is sufficient to induce progressively worsening symptoms of Parkinsons disease that are not shared with Alzheimers disease (Gonzalez-Rodriguez et al., 2021)

The April 2026 Announcement: What It Says The FDA's April 2026 announcement removed 12 peptides from Category 2 status

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Saini et al., 2023)