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(iii) the branched-chain -ketoacid dehydrogenase complex that is involved in the decarboxylation of ketoacids in the catabolic pathway of the branched-chain amino acids, namely leucine, isoleucine, and valine

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Subjective daytime fatigue and sleepiness were decreased on day 1 and objective measures of alertness were improved on days 13 during glycine use compared with placebo, suggesting glycine may mitigate some consequences of acute sleep loss

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Analysts struck a measured tone

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Nausea (44%) Most common in weeks 1 to 4 during dose titration

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Clinical trial doses have ranged from 1 mg to 12 mg injected once weekly

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