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As with any emerging pharmacological agent, the establishment of a safe and effective dosage for clinical use necessitates thorough and rigorous clinical trials

doi:10.1002/1099-0690(200301)2003:1 3.0.CO;2-I

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Symptoms of iron deficiency anemia often ease sooner, within a week or month. Other research suggests that intermittent iron supplementation (as opposed to daily) may bring the same benefits with fewer side effects. Higher amounts are usually spread across two daily doses for better absorption. Iron absorbs best on an empty stomach, but taking it this way can create digestive upset