Figure 3 Having demonstrated that metformin treatment alone induces cell death in both HCT116 and SW837 cells, the impact of metformin combined with a clinically-relevant dose of 1.8 Gy radiation was assessed at 48 h post radiation exposure
Dr Martin Juneau, M.D., FRCP Cardiologue, directeur de l'Observatoire de la prvention de l'Institut de Cardiologie de Montral
It has been shown that free radicals ( Reference Ambrosio, Flaherty and Duilio 50 , Reference Bolli, Zughaib and Li 51 ) and inflammatory cytokines ( Reference Kukielka, Smith and Manning 52 ) have a key role in reperfusion injury process
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doi: 10.1016/S0140-6736(06)68073-2 98 NaessHSundalEMyhrKMNylandHI