Second, as mentioned above, c-Met inhibitors which target the interaction between HGF and c-Met may lose efficacy owing to cell attachment (Wang et al., 2001), gene amplification of c-Met, DCP binding to c-Met (Suzuki et al., 2005), gene mutation in the c-Met activation loop (Okuma and Kondo, 2016) and crosstalk with other membrane receptors (Garcia-Vilas and Medina, 2018)
Last reviewed: May 2026
Body protective compound-157 enhances alkali-burn wound healing In Vivo and promotes proliferation, migration, and angiogenesis in vitro
Safety considerations and contraindications Peptides used for allergic conditions generally have favorable safety profiles, but they are not without considerations
Mouse studies reported changes in adiposity, glucose handling, liver pathology and muscle-function measurements