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Aging and plasminogen activator inhibitor-1 (PAI-1) regulation: implication in the pathogenesis of thrombotic disorders in the elderly

Within the iron-rich, ROS-prone microenvironment of EMS, inhibition of system Xc limits cystine import, depletes GSH, constrains GPX4 activity, and drives lipid peroxidation in ectopic endometrial stromal cells

It is not approved by the Therapeutic Goods Administration for human therapeutic use and is not a registered medicine

Start low and be prepared to stop if symptoms or lab changes appear

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