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This result was further validated by treating human THP-1 macrophages with the human v3 integrin blocking antibody LM609

One group, mapping to innate immunity and antiviral responses (Oas2, Oas3, Mx2, Irf7, Irf9, STAT1, il1b), required GSH for optimal induction

A subcutaneous infection near the knee causes redness, swelling, and warmth within 48-72 hours, potentially requiring antibiotics and forcing you to stop the entire protocol

Murine models of hypertension Hypertension mouse models were generated by Angiotensin-II (1000 ng/kg/min) infusion using osmotic pumps (DURECT, Alzet model 2004), which were implanted subcutaneously in 1216 weeks-old C57Bl/6 mice for 28 days