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The key issue here is that this is a therapeutic procedure, not merely a sampling procedure

This requires: Rapid cell division (for skin cells, fibroblasts, and endothelial cells) Adequate oxygen delivery to the wound bed Collagen synthesis and cross-linking Immune function to prevent infection Vitamin B12 contributes directly to the first two of these, and indirectly to the others

You have 28 days of usable solution when stored properly in the refrigerator

Reconstituted vials stable 28 days at 2 C8 C

An increase in the expression of AT 1 receptors and decreased expression of AT 2 receptors has been reported in aged rats (130)