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Because of this, lots of people have mild to moderate vitamin B12 deficiencies due to unbalanced diets or other factors

Other Pine Bark Extracts There is some evidence that pine bark extract may help improve circulation and chronic venous insufficiency, but be aware that some supplements are not like those used in most clinical trials

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This suggests that it might be more beneficial to check red blood cell folate instead of serum folate in people with Down syndrome