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RBCs stored with E-Sol5 showed increased glycolysis and higher ratios of reduced to oxidized glutathione compared to SAGM

Barbalace MC, Malaguti M, Giusti L, Lucacchini A, Hrelia S, Angeloni C

Acute toxicity studies in animals, if extrapolated to humans, implicate a single dose of 10-15 grams necessary to produce significant liver toxicity, although several human case reports have shown toxicity at doses less than 4 grams per day (likely due to having one or more risk factors for sensitivity to toxicity) (Amar 2007)

Esterline RL, Ji S

[DOI] [PMC free article] [PubMed] [Google Scholar] 172.Rautio J., Kumpulainen H., Heimbach T., Oliyai R., Oh D., Jrvinen Jo T., Savolainen J