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This gastrointestinal side effect occurs because semaglutide activates GLP-1 receptors in the gut, deliberately slowing the rate at which food moves through your digestive systemthe same mechanism that reduces appetite and improves blood sugar control

Potential Challenges: Side Effects and Donation The primary reason a person on Ozempic might be turned away from a plasma donation center isnt the drug itself, but rather the semaglutide side effects and management the drug can cause

Semaglutide and tirzepatide do not damage hair follicles

Ozempic *Results achieved at the highest allowed dose of each medication

Similarly, rectal bleeding or black, tarry stools should never be attributed to constipation alone and necessitate prompt evaluation to rule out gastrointestinal bleeding or other pathology