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Circulation 145 , 18531866 (2022)

The Adverse Events in FDAs Review Three FAERS reports were discussed FDAs briefing describes reports in its Adverse Event Reporting System involving an injection-site reaction, shortness of breath, diffuse skin darkening, and gum darkening

Therefore, clinicians must take a careful and individualized approach when prescribing these agents for this patient population

Symptoms can be categorised into local (injection site) and systemic manifestations, with varying degrees of severity